Yes, many portable speakers with lights can sync their effects to music, but the exact behaviour depends on the lighting controller and companion app. Beat-sync modes analyse the music signal and vary colour, brightness, or movement, while preset scenes simply run a repeating pattern without following the song.
Some speakers analyse the audio internally, so synchronisation also works with FM, AUX, or local playback; others use an app or microphone and respond to sound in the room. Microphone-based modes can react to voices and background noise, whereas direct signal analysis is usually tighter for Bluetooth playback.
The response is easiest to notice with a strong beat and moderate volume. Very slow songs, distorted playback, or heavy room noise can make effects look late or erratic, and the LEDs may follow bass energy rather than every musical detail.
Look for adjustable sensitivity, speed, brightness, and a static-colour option if the speaker will also be used for normal listening. A sync feature is more useful when it can be disabled quickly, saved as a separate scene, and used without forcing the loudest or most distracting flash pattern.