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ASUS ProArt Mouse MD300 Review | 78 Data compared

Avg. price: ~£45
Connectivity: wireless+wired
Maximum polling rate: 1000 Hz
Maximum DPI: 4200 DPI
Weight: 109 g

ASUS ProArt Mouse MD300 review. Compare 78 technical specifications and user reviews to see how it ranks among mice and if it is worth buying.

6.6

Good

6.8

Good

5.9

Good

5.9
Gaming
Score components:
28.0%
3.7
Maximum polling rate
24.0%
7.8
N. of programmable buttons
20.0%
9.0
Onboard memory profiles
16.0%
4.2
Maximum tracking speed
12.0%
4.7
Weight

Best prices in UK

£?

Best rankings

#24 in Best ASUS Mice
#320 in Best Computer Mice

Verdict

The ASUS ProArt Mouse MD300 is a specialized wireless peripheral designed for creative professionals, featuring a high-performance laser sensor with up to 4,200 DPI that tracks accurately even on glass surfaces. Its defining characteristic is the integrated ASUS Dial and a side scroll wheel, providing intuitive control over over 80 functions in apps like Adobe Photoshop and Premiere Pro, complemented by an independent large middle button for CAD workflows. Built for durability, it uses professional-grade Omron switches rated for 50 million clicks and offers versatile connectivity via 2.4 GHz RF or Bluetooth for up to three devices. Main pros include its exceptional 150-day battery life, fast-charging capabilities (3 hours of use from a 1-minute charge), and ergonomic design with a dedicated thumb rest. However, notable cons include its high price point, the lack of dedicated back/forward side buttons, and limited software compatibility for macOS users.

Technical Specifications of ASUS ProArt Mouse MD300

Overall score

6.6

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Popularity

What it is: An indicator based on the number of reviews received by the mouse.

When it matters: When you prefer a mouse that has already been chosen and reviewed by many other users.

Performance & Sensor

6.0

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Brand name

What it is: The manufacturer or brand of the product.

When it matters: When you prefer a specific ecosystem, support network, or design philosophy.

Importance: MEDIUM

Asus

Maximum polling rate

What it is: The maximum number of position reports the mouse can send to the computer each second, measured in Hertz (Hz).

When it matters: When you are chasing the lowest possible input delay for competitive play and want the mouse reporting as often as possible.

Importance: HIGH

Good value: >=1000 Hz

Wired polling rate

What it is: The polling rate the mouse reaches when it is connected with a cable.

When it matters: When you mainly use the mouse wired and want maximum responsiveness.

Importance: HIGH

Good value: >=1000 Hz

2.4 GHz polling rate

What it is: The polling rate available when the mouse is used over a 2.4 GHz wireless connection.

When it matters: When you use the 2.4 GHz receiver and want near-wired performance.

Importance: HIGH

Good value: >=1000 Hz

Bluetooth polling rate

What it is: The polling rate available when the mouse is connected through Bluetooth.

When it matters: When you use Bluetooth and want to understand the trade-off in responsiveness.

Importance: LOW

Good value: >=125 Hz

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Connectivity

10

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Connectivity

What it is: The mouse's high-level connectivity class: wired only, wireless only, or both wired and wireless.

When it matters: When you need to know at a glance whether the mouse is wired, wireless, or flexible enough to support both.

Importance: HIGH

Bluetooth support

What it is: Shows whether the mouse can connect over Bluetooth instead of relying only on a wired link or proprietary USB receiver.

When it matters: When you want a dongle-free connection option for laptops, tablets, or devices with limited USB ports.

Importance: MEDIUM

Bluetooth version

What it is: The Bluetooth standard version supported by the mouse for wireless connectivity and compatibility.

When it matters: When you care about Bluetooth compatibility, efficiency, and connection quality.

Importance: LOW

Good value: >=5.1

Proprietary 2.4 GHz support

What it is: Shows whether the mouse supports the brand's dedicated 2.4 GHz wireless system rather than relying only on Bluetooth.

When it matters: When you want the brand's fast low-latency wireless mode instead of depending only on Bluetooth performance.

Importance: MEDIUM

Receiver included

What it is: Shows whether a compatible wireless receiver is included in the box instead of needing to be bought separately.

When it matters: When you expect full wireless use immediately and do not want to buy extra accessories just to get started.

Importance: MEDIUM

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Battery & Charging

9.4

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Battery life

What it is: The operating time the mouse can deliver on a full charge or a fresh set of batteries under normal use.

When it matters: When the mouse needs to last through workdays, travel, or repeated gaming sessions without constant charging.

Importance: HIGH

Good value: >400 hours

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Battery capacity

What it is: The amount of energy the built-in battery can store, measured in milliampere-hours (mAh).

When it matters: When you want rough battery context behind the runtime claim instead of judging endurance from marketing hours alone.

Importance: MEDIUM

Good value: >=500 mAh

Battery form factor

What it is: The battery format used by the mouse, such as AA, AAA, integrated rechargeable cell, or another form.

When it matters: When you care whether the mouse uses easy-to-replace AA or AAA cells or a sealed rechargeable pack.

Importance: LOW

integrated

Rechargeable battery

What it is: Shows whether the mouse uses a rechargeable battery instead of relying only on disposable cells.

When it matters: When you prefer topping the mouse up over USB or a dock instead of buying disposable batteries repeatedly.

Importance: HIGH

Removable battery

What it is: Shows whether the battery can be removed and replaced by the user instead of being sealed inside the mouse.

When it matters: When long-term serviceability matters and you would rather replace the battery than replace the whole mouse later.

Importance: LOW

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Controls

6.4

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N. of buttons

What it is: The total number of physical buttons available on the mouse body.

When it matters: When you need enough physical controls for shortcuts, MMO binds, browser actions, or productivity commands.

Importance: HIGH

Good value: >=7

N. of side buttons

What it is: The number of buttons placed on the side of the mouse, typically for thumb access.

When it matters: When thumb-access buttons matter for browser navigation, MMOs, or productivity shortcuts.

Importance: MEDIUM

Good value: >=2

N. of programmable buttons

What it is: The number of mouse buttons that can be customized or reassigned through software or onboard settings.

When it matters: When remapping flexibility matters and you want more actions moved off the keyboard.

Importance: HIGH

Good value: >=7

DPI switching button

What it is: Shows whether the mouse includes a dedicated control for changing DPI levels on the fly.

When it matters: When you want to swap sensitivity instantly for sniping, browsing, editing, or different game genres.

Importance: MEDIUM

Profile switching button

What it is: Shows whether the mouse includes a dedicated control for changing onboard or saved profiles during use.

When it matters: When you switch between saved profiles for different games or work routines.

Importance: LOW

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Design

5.4

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Orientation

What it is: The hand orientation the mouse is designed for, such as right-handed, left-handed, or ambidextrous use.

When it matters: When hand comfort matters and you need a shape that fits your grip and dominant hand.

Importance: HIGH

right-handed

Weight

What it is: The overall weight of the mouse itself, which influences portability, comfort, and movement feel.

When it matters: When you care about how light or substantial the mouse feels during long sessions.

Importance: HIGH

Good value: <100 g

Extra weights

What it is: The total weight of removable extra weights included for tuning the balance or feel of the mouse.

When it matters: When you care about tuning balance and overall heft instead of being locked into the stock feel.

Importance: LOW

Cable length

What it is: The length of the supplied cable used for wired operation or charging, usually measured in meters.

When it matters: When you need enough cable reach across your desk or charging setup.

Importance: LOW

Good value: >=1.8 m

Cable type

What it is: The construction style of the cable, such as braided, rubber, or paracord, which affects flexibility and durability.

When it matters: When cable drag, flexibility, and durability affect how the mouse feels in use.

Importance: LOW

rubber

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Features

8.5

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Onboard memory profiles

What it is: The number of user profiles that can be stored directly in the mouse memory for use without reconfiguring software each time.

When it matters: When you use different games, apps, or devices and want settings saved directly on the mouse.

Importance: MEDIUM

Good value: >=3

?

Onboard memory size

What it is: The amount of onboard memory available inside the mouse for storing settings, macros, or profiles.

When it matters: When you store complex macros, settings, or several onboard profiles.

Importance: LOW

Good value: >=512 KB

?

Software name

What it is: The name of the official software used to configure the mouse, update firmware, or customize features.

When it matters: When software ecosystem and customization tools influence your buying decision.

Importance: LOW

Armoury Crate Gear

Firmware upgradable

What it is: Shows whether the mouse can receive firmware updates for fixes, compatibility improvements, or feature changes.

When it matters: When you want the option for later fixes, stability improvements, or performance tweaks after purchase.

Importance: LOW

Suitable for gaming

What it is: Shows whether the mouse is positioned or tuned around gaming-focused speed, latency, and control features.

When it matters: When fast clicks, low latency, and gaming-oriented features are priorities.

Importance: MEDIUM

ASUS ProArt Mouse MD300 vs the average mouse

Why is ASUS ProArt Mouse MD300 better than the average mouse?

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Adjustable lift-off distance
ASUS ProArt Mouse MD300 supports adjustable lift-off distance, while the average mouse does not. 46.5% of mice support adjustable lift-off distance.
What it is: Shows whether you can tune how high the mouse can be lifted before the sensor stops tracking movement.
When it matters: When you lift and reposition the mouse often and want tighter cursor control.
Importance: MEDIUM
ASUS ProArt Mouse MD300 supports adjustable lift-off distance, while the average mouse does not. 46.5% of mice support adjustable lift-off distance.
Usable while charging
ASUS ProArt Mouse MD300 can be used while charging, while the average mouse cannot. 47.5% of mice can be used while charging.
What it is: Shows whether the mouse keeps working normally while a charging cable is connected.
When it matters: When you do not want downtime while the mouse battery is charging.
Importance: MEDIUM
ASUS ProArt Mouse MD300 can be used while charging, while the average mouse cannot. 47.5% of mice can be used while charging.
20 million clicks longer switch lifespan
ASUS ProArt Mouse MD300 offers switch durability of 50 million clicks, while the average mouse offers switch durability of 30 million clicks.
Omron switches.
What it is: The rated click lifespan of the primary switches, usually expressed in millions of clicks.
When it matters: When heavy clicking, long-term reliability, and avoiding early switch failure are part of the buying decision.
Importance: MEDIUM
Good value: >=70 million clicks
ASUS ProArt Mouse MD300 offers switch durability of 50 million clicks, while the average mouse offers switch durability of 30 million clicks.50 million clicks vs 30 million clicks
Thumb scroll wheel
ASUS ProArt Mouse MD300 includes a thumb scroll wheel, while the average mouse does not. 2% of mice include a thumb scroll wheel.
What it is: Shows whether the mouse includes a secondary scroll wheel positioned for thumb use.
When it matters: When side scrolling, timeline control, or spreadsheet work would benefit from a wheel under your thumb.
Importance: LOW
ASUS ProArt Mouse MD300 includes a thumb scroll wheel, while the average mouse does not. 2% of mice include a thumb scroll wheel.
2 more paired devices
ASUS ProArt Mouse MD300 pairs with 3 devices, while the average mouse pairs with 1 devices.
What it is: The maximum number of devices the mouse can stay paired with for switching between them.
When it matters: When you regularly swap the same mouse between several paired devices.
Importance: LOW
Good value: >=2
ASUS ProArt Mouse MD300 pairs with 3 devices, while the average mouse pairs with 1 devices.3 vs 1
Multi-device pairing
ASUS ProArt Mouse MD300 supports multi-device pairing, while the average mouse does not. 21.1% of mice support multi-device pairing.
up to 3 devices.
What it is: Shows whether the mouse can stay paired with more than one device for quicker switching.
When it matters: When you switch between a laptop, desktop, and tablet with the same mouse.
Importance: MEDIUM
ASUS ProArt Mouse MD300 supports multi-device pairing, while the average mouse does not. 21.1% of mice support multi-device pairing.
Rechargeable battery
ASUS ProArt Mouse MD300 uses a rechargeable battery, while the average mouse does not. 46% of mice use a rechargeable battery.
What it is: Shows whether the mouse uses a rechargeable battery instead of relying only on disposable cells.
When it matters: When you prefer topping the mouse up over USB or a dock instead of buying disposable batteries repeatedly.
Importance: HIGH
ASUS ProArt Mouse MD300 uses a rechargeable battery, while the average mouse does not. 46% of mice use a rechargeable battery.
Detachable cable
ASUS ProArt Mouse MD300 comes with a detachable cable, while the average mouse does not. 42.9% of mice come with a detachable cable.
What it is: Shows whether the cable can be unplugged and replaced instead of staying permanently attached to the mouse.
When it matters: When you value easier cable replacement, transport, or long-term repairability.
Importance: LOW
ASUS ProArt Mouse MD300 comes with a detachable cable, while the average mouse does not. 42.9% of mice come with a detachable cable.
Adjustable lift-off distance
ASUS ProArt Mouse MD300 supports adjustable lift-off distance, while the average mouse does not. 46.5% of mice support adjustable lift-off distance.
100 DPI lower minimum setting
ASUS ProArt Mouse MD300 goes as low as 100 DPI DPI, while the average mouse goes as low as 200 DPI DPI.
2 more paired devices
ASUS ProArt Mouse MD300 pairs with 3 devices, while the average mouse pairs with 1 devices.
Multi-device pairing
ASUS ProArt Mouse MD300 supports multi-device pairing, while the average mouse does not. 21.1% of mice support multi-device pairing.
Versatile connectivity
ASUS ProArt Mouse MD300 supports wireless+wired connectivity, while the average mouse supports wireless connectivity.
Bluetooth support
ASUS ProArt Mouse MD300 supports Bluetooth, while the average mouse does not. 35.5% of mice support Bluetooth.
Receiver storage inside mouse
ASUS ProArt Mouse MD300 has receiver storage inside the mouse, while the average mouse does not. 45.9% of mice have receiver storage inside the mouse.
Usable while charging
ASUS ProArt Mouse MD300 can be used while charging, while the average mouse cannot. 47.5% of mice can be used while charging.
Rechargeable battery
ASUS ProArt Mouse MD300 uses a rechargeable battery, while the average mouse does not. 46% of mice use a rechargeable battery.
Wireless charging
ASUS ProArt Mouse MD300 supports wireless charging, while the average mouse does not. 10.6% of mice support wireless charging.
60% larger battery capacity
ASUS ProArt Mouse MD300 has a battery capacity of 800 mAh, while the average mouse has a battery capacity of 500 mAh.
20 million clicks longer switch lifespan
ASUS ProArt Mouse MD300 offers switch durability of 50 million clicks, while the average mouse offers switch durability of 30 million clicks.
Thumb scroll wheel
ASUS ProArt Mouse MD300 includes a thumb scroll wheel, while the average mouse does not. 2% of mice include a thumb scroll wheel.
Detachable cable
ASUS ProArt Mouse MD300 comes with a detachable cable, while the average mouse does not. 42.9% of mice come with a detachable cable.
75.4 mm shorter mouse length
ASUS ProArt Mouse MD300 is 42.9 mm long, while the average mouse is 118.3 mm long.

Performance & Sensor

Battery & Charging

Why is ASUS ProArt Mouse MD300 worse than the average mouse?

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58% lower maximum DPI
ASUS ProArt Mouse MD300 has a maximum DPI of 4,200 DPI, while the average mouse has a maximum DPI of 10,000 DPI.
37.5% lower tracking speed
ASUS ProArt Mouse MD300 has a maximum tracking speed of 250 IPS, while the average mouse has a maximum tracking speed of 400 IPS.
2 fewer stored DPI steps
ASUS ProArt Mouse MD300 stores 3 DPI steps, while the average mouse stores 5 DPI steps.
2 fewer side buttons
ASUS ProArt Mouse MD300 has 0 side buttons, while the average mouse has 2 side buttons.
Uses a side scroll wheel / ASUS Dial instead of traditional side buttons.
31.7% higher mouse weight
ASUS ProArt Mouse MD300 weighs 109 g, while the average mouse weighs 82.745 g.
No RGB lighting
ASUS ProArt Mouse MD300 does not have RGB lighting, while the average mouse does. 56.3% of mice have RGB lighting.
2.3 mm taller mouse height
ASUS ProArt Mouse MD300 has a height of 42 mm, while the average mouse has a height of 39.7 mm.
6 mm wider mouse width
ASUS ProArt Mouse MD300 has a width of 72 mm, while the average mouse has a width of 66 mm.
Not suitable for gaming
ASUS ProArt Mouse MD300 is not suitable for gaming, while the average mouse is. 75.8% of mice are suitable for gaming.
31.7% higher mouse weight
ASUS ProArt Mouse MD300 weighs 109 g, while the average mouse weighs 82.745 g.
What it is: The overall weight of the mouse itself, which influences portability, comfort, and movement feel.
When it matters: When you care about how light or substantial the mouse feels during long sessions.
Importance: HIGH
Good value: <100 g
ASUS ProArt Mouse MD300 weighs 109 g, while the average mouse weighs 82.745 g.109 g vs 82.745 g
Not suitable for gaming
ASUS ProArt Mouse MD300 is not suitable for gaming, while the average mouse is. 75.8% of mice are suitable for gaming.
What it is: Shows whether the mouse is positioned or tuned around gaming-focused speed, latency, and control features.
When it matters: When fast clicks, low latency, and gaming-oriented features are priorities.
Importance: MEDIUM
ASUS ProArt Mouse MD300 is not suitable for gaming, while the average mouse is. 75.8% of mice are suitable for gaming.
58% lower maximum DPI
ASUS ProArt Mouse MD300 has a maximum DPI of 4,200 DPI, while the average mouse has a maximum DPI of 10,000 DPI.
What it is: The highest sensitivity setting supported by the mouse sensor, measured in dots per inch (DPI).
When it matters: When extremely high sensitivity is part of your setup, even if it matters less than sensor quality for most users.
Importance: HIGH
Good value: >=18000 DPI
ASUS ProArt Mouse MD300 has a maximum DPI of 4,200 DPI, while the average mouse has a maximum DPI of 10,000 DPI.4200 DPI vs 10000 DPI
37.5% lower tracking speed
ASUS ProArt Mouse MD300 has a maximum tracking speed of 250 IPS, while the average mouse has a maximum tracking speed of 400 IPS.
What it is: The highest movement speed the sensor can track accurately before it starts losing precision, usually expressed in inches per second (IPS).
When it matters: When you make very fast swipes and do not want the sensor to lose tracking.
Importance: HIGH
Good value: >=400 IPS
ASUS ProArt Mouse MD300 has a maximum tracking speed of 250 IPS, while the average mouse has a maximum tracking speed of 400 IPS.250 IPS vs 400 IPS
2 fewer side buttons
ASUS ProArt Mouse MD300 has 0 side buttons, while the average mouse has 2 side buttons.
Uses a side scroll wheel / ASUS Dial instead of traditional side buttons.
What it is: The number of buttons placed on the side of the mouse, typically for thumb access.
When it matters: When thumb-access buttons matter for browser navigation, MMOs, or productivity shortcuts.
Importance: MEDIUM
Good value: >=2
ASUS ProArt Mouse MD300 has 0 side buttons, while the average mouse has 2 side buttons.0 vs 2
No RGB lighting
ASUS ProArt Mouse MD300 does not have RGB lighting, while the average mouse does. 56.3% of mice have RGB lighting.
What it is: Shows whether the mouse includes RGB lighting for visual effects or ecosystem syncing.
When it matters: When visual customization, ecosystem sync, or a specific desk aesthetic matters as much as raw function.
Importance: LOW
ASUS ProArt Mouse MD300 does not have RGB lighting, while the average mouse does. 56.3% of mice have RGB lighting.
36.1% lower user score
ASUS ProArt Mouse MD300 has a lower user score than the average mouse (5.88 vs 8.000).
What it is: A rating that combines user reviews and the total number of reviews received by the mouse.
When it matters: When you want to understand how a mouse performs in daily use or gaming and how reliable it is in terms of comfort, button feel, tracking accuracy, and long-term durability.
ASUS ProArt Mouse MD300 has a lower user score than the average mouse (5.88 vs 8.000).5.88 vs 8
2 fewer stored DPI steps
ASUS ProArt Mouse MD300 stores 3 DPI steps, while the average mouse stores 5 DPI steps.
What it is: The number of different DPI levels that can be saved and recalled on the mouse.
When it matters: When you switch sensitivity often and want several presets ready without opening software every time.
Importance: MEDIUM
Good value: >=5
ASUS ProArt Mouse MD300 stores 3 DPI steps, while the average mouse stores 5 DPI steps.3 vs 5

Performance & Sensor

Graphic comparison of ASUS ProArt Mouse MD300 and

Attribute category

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Third-party reviews

United Kingdom

(Reviews last updated: May 2026)

What customers like about ASUS ProArt Mouse MD300?

Unique physical Asus Dial and side scroll wheel specifically optimized for Adobe Creative Suite workflows
Exceptional battery life lasting up to 150 days on a single charge
Extremely fast charging, providing 3 hours of heavy use from just a one-minute charge
Premium build quality featuring professional-grade, replaceable Omron switches and metallic wheels
Versatile connectivity with support for 2.4GHz RF and pairing with up to three Bluetooth devices
Reliable tracking on almost any surface, including glass, thanks to its high-performance sensor

What customers dislike about ASUS ProArt Mouse MD300?

Software limitations as the primary customization app, Armoury Crate, is exclusive to Windows
High price point compared to other productivity mice with similar core features
Lack of a free-spin/infinite scroll mode on the main wheel, which can make long document navigation tedious
The onscreen Dial UI can be intrusive, appearing too large on non-4K displays or being difficult to dismiss
Missing dedicated 'back' and 'forward' thumb buttons commonly found on other productivity mice
Bluetooth connectivity can occasionally be finicky or require re-pairing on certain systems

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