MSI X399 SLI Plus Review | 107 Data compared

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  • Avg. price: ~£220
  • CPU socket: TR4
  • Chipset: AMD X399
  • Form factor: ATX

MSI X399 SLI Plus review. Compare 107 technical specifications and user reviews to see how it ranks among motherboards and if it is worth buying.

6.7

Overall score

What it is: An overall evaluation of the motherboard's quality, based on technical analyses and user reviews.

When it matters: When you need a quick reference to identify the best motherboards on the market.

Score components:

90.0%

6.7

Technical Score

10.0%

7.3

User score

Good
6.7

Technical Score

What it is: An assessment of the motherboard's technical performance, covering key areas such as power delivery, CPU and memory support, expansion, storage, connectivity, cooling, BIOS features, and design.

When it matters: When you want to compare motherboards based on technical performance and available features.

Score components:

19.0%

7.0

Memory

16.0%

6.9

Platform & Features

16.0%

6.4

Storage

15.0%

5.5

Network

13.0%

6.6

Ports & USB

8.0%

5.5

Expansion

8.0%

7.8

Power & Cooling

5.0%

9.2

Audio

Good
7.3

User score

What it is: A rating that combines user reviews and the total number of reviews received by the motherboard.

When it matters: When you want to understand how a motherboard performs in real-world builds and how reliable it is in terms of stability, BIOS usability, connectivity, and long-term ownership.

Score components:

70.0%

7.7

User reviews

30.0%

6.3

Popularity

User score:
United Kingdom
amazon
4.0
(104)
amazon
3.6
(22)
United States
Amazon_logo.png
3.9
(124)

(Reviews last updated: May 2026)

Very good
  • 5.2
    Gaming

    Score components:

    28.0%

    6.7

    VRM phases

    22.0%

    7.8

    N. of M.2 sockets

    18.0%

    4.6

    LAN speed

    17.0%

    3.8

    Maximum RAM speed

    15.0%

    1.0

    N. of PCIe 5.0 x16 slots

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Best prices in UK

Best rankings

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Available: ranking among products currently available (including other versions of this product).
All: ranking among all products in the database.

Verdict

The MSI X399 SLI PLUS is an ATX motherboard built on the AMD X399 chipset, supporting 1st and 2nd Gen Ryzen Threadripper processors via the sTR4 socket. It features a professional all-black aesthetic and is equipped with eight DDR4 DIMM slots supporting up to 128GB of quad-channel memory at speeds reaching 3600MHz+ (OC). Key technical specifications include four PCIe 3.0 x16 slots with Steel Armor supporting up to 4-way NVIDIA SLI or AMD CrossFire, three Turbo M.2 slots (32Gb/s) with a thermal shield, eight SATA 6Gb/s ports, and a 13-phase DrMOS power design. Pros include its robust VRM quality for stable overclocking, extensive high-speed connectivity with USB 3.1 Gen2 Type-A and Type-C, and integrated Mystic Light RGB for customisation. Main cons involve the lack of built-in Wi-Fi and occasional reported BIOS stability issues with high-core-count processors like the 2990WX during extreme overclocking.

Technical Specifications of MSI X399 SLI Plus

Technical Score

What it is: An assessment of the motherboard's technical performance, covering key areas such as power delivery, CPU and memory support, expansion, storage, connectivity, cooling, BIOS features, and design.

When it matters: When you want to compare motherboards based on technical performance and available features.

Score components:

19.0%

7.0

Memory

16.0%

6.9

Platform & Features

16.0%

6.4

Storage

15.0%

5.5

Network

13.0%

6.6

Ports & USB

8.0%

5.5

Expansion

8.0%

7.8

Power & Cooling

5.0%

9.2

Audio

6.7
MSI X399 SLI Plus has a technical score of 6.65 points, which is higher than that of 56% of products in this category.
User score

What it is: A rating that combines user reviews and the total number of reviews received by the motherboard.

When it matters: When you want to understand how a motherboard performs in real-world builds and how reliable it is in terms of stability, BIOS usability, connectivity, and long-term ownership.

Score components:

70.0%

7.7

User reviews

30.0%

6.3

Popularity

User score:
United Kingdom
amazon
4.0
(104)
amazon
3.6
(22)
United States
Amazon_logo.png
3.9
(124)

(Reviews last updated: May 2026)

7.3
MSI X399 SLI Plus has a user score of 7.27 points, which is lower than that of 71% of products in this category.
Popularity
What it is: An indicator based on the number of reviews received by the motherboard.
When it matters: When you prefer a motherboard that has already been bought and reviewed by many other users.
6.3
MSI X399 SLI Plus has a popularity of 6.3 points, which is higher than 65.4% of products in this category.
Ratio quality/price

What it is: An indicator that combines the motherboard's overall rating with its cost.

When it matters: When you are looking for a motherboard that offers a strong balance of features, performance, and price.

Score components:

60.0%

6.7

Overall score

40.0%

9.4

Price

7.5
MSI X399 SLI Plus has a quality-to-price ratio of 7.5 points, which is higher than 54% of products in this category.
Brand name
What it is: The brand that makes the motherboard.
When it matters: When you have a brand preference for support, BIOS, or build quality.

Importance: MEDIUM

MSI
CPU socket
What it is: The socket type the motherboard is built to support.
When it matters: When you need the motherboard to match a specific CPU.

Importance: HIGH

TR4
MSI X399 SLI Plus uses the TR4 CPU socket, which is more advanced than that of 53.8% of motherboards and equal to that of 0.5% of motherboards.
CPU platform

Importance: MEDIUM

AMD
Chipset
What it is: The chipset that defines the motherboard platform and many of its features.
When it matters: When you compare platform features, connectivity, and CPU support.

Importance: HIGH

AMD X399
MSI X399 SLI Plus uses the AMD X399 chipset, which is less advanced than that of 64.8% of motherboards and equal to that of 0.5% of motherboards.
Form factor
What it is: The physical size standard of the motherboard, such as ATX or Micro-ATX.
When it matters: When you need the board to fit a specific case size.

Importance: HIGH

ATX
MSI X399 SLI Plus has the ATX form factor, which is more versatile than that of 47.8% of motherboards and equal to that of 52.2% of motherboards.
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DDR memory version
What it is: The RAM generation the motherboard supports, such as DDR4 or DDR5.
When it matters: When you need the board to match a certain memory platform.

Importance: HIGH

Good value: DDR5

DDR4
MSI X399 SLI Plus uses DDR4 memory, which is newer than that of 13.6% of motherboards and equal to that of 51% of motherboards.
Memory slots
What it is: The number of RAM slots on the motherboard.
When it matters: When you want more room for future memory upgrades.

Importance: HIGH

Good value: >=4

8
MSI X399 SLI Plus has 8 Memory slots, which is more than 94% of motherboards and equal to 5.7% of motherboards.
Maximum memory capacity
What it is: The largest total amount of RAM the motherboard supports.
When it matters: When you plan a build with very high memory capacity.

Importance: HIGH

Good value: >=128 GB

128 GB
MSI X399 SLI Plus supports up to 128 GB of memory, which is more than 40.4% of motherboards and equal to 32.1% of motherboards.
Memory channels
What it is: The memory channel configuration supported by the motherboard platform.
When it matters: When memory bandwidth matters for your build.

Importance: MEDIUM

4
MSI X399 SLI Plus supports 4 memory channels, which is more than 92.8% of motherboards and equal to 6.9% of motherboards.
Maximum RAM speed
What it is: The highest officially supported memory speed for the motherboard.
When it matters: When you choose RAM and want to know the supported speed ceiling.

Importance: HIGH

Good value: >=6400 MT/s

3,600 MT/s
MSI X399 SLI Plus supports memory speeds up to 3600 MT/s, which is lower than that of 59.2% of motherboards and equal to that of 1.6% of motherboards.
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N. of M.2 sockets
What it is: The number of M.2 slots available on the motherboard.
When it matters: When you want room for more NVMe or M.2 drives.

Importance: HIGH

Good value: >=3

3
MSI X399 SLI Plus has 3 M.2 sockets, which is more than 65.4% of motherboards and equal to 18.6% of motherboards.
M.2 slot interface per slot
What it is: The storage or PCIe interface available for each M.2 slot on the motherboard.
When it matters: When you want to check which drives each M.2 slot can use.

Importance: HIGH

?
N. of SATA 3 connectors
What it is: The number of SATA 6Gb/s connectors on the motherboard.
When it matters: When you plan to connect multiple SATA drives.

Importance: MEDIUM

Good value: >=6

8
MSI X399 SLI Plus has 8 SATA 3 connectors, which is more than 85.5% of motherboards and equal to 11.2% of motherboards.
Supported RAID levels
What it is: The RAID modes officially supported by the motherboard storage platform.
When it matters: When you plan to use multiple drives in a RAID setup.

Importance: MEDIUM

0/1/10
MSI X399 SLI Plus supports RAID levels 0/1/10, which is narrower than 68.3% of motherboards and equal to 23.2% of motherboards.
JBOD excluded from RAID-level set
NVMe RAID support
What it is: Shows whether the board supports RAID configurations that use NVMe SSDs.
When it matters: When you plan to use multiple NVMe drives in RAID.

Importance: LOW

yes
MSI X399 SLI Plus supports NVMe RAID. 40.3% of motherboards support this feature.
requires RAID drivers
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N. of PCIe 5.0 x16 slots
What it is: The number of PCIe 5.0 x16 physical slots on the motherboard.
When it matters: When you want the newest high-bandwidth expansion slots.

Importance: HIGH

Good value: >=1

0
MSI X399 SLI Plus has 0 PCIe 5.0x16 slots, which is equal to 68.5% of motherboards.
N. of PCIe 4.0 x16 slots
What it is: The number of PCIe 4.0 x16 physical slots on the motherboard.
When it matters: When you want more room for modern expansion cards.

Importance: HIGH

Good value: >=1

0
MSI X399 SLI Plus has 0 PCIe 4.0x16 slots, which is equal to 55.6% of motherboards.
N. of PCIe 3.0 x16 slots
What it is: The number of PCIe 3.0 x16 physical slots on the motherboard.
When it matters: When you need more full-length expansion slots.

Importance: MEDIUM

4
MSI X399 SLI Plus has 4 PCIe 3.0x16 slots, which is more than 93.9% of motherboards and equal to 3.5% of motherboards.
PCIe slot electrical configuration
What it is: The actual lane wiring used by the motherboard PCIe slots.
When it matters: When you need to know how much bandwidth each slot really gets.

Importance: HIGH

x16/x8/x16/x8, x16/x0/x16/x8, x8/x8/x16/x8
MSI X399 SLI Plus uses x16/x8/x16/x8, x16/x0/x16/x8, x8/x8/x16/x8 for PCIe slot electrical configuration, which is more flexible than that of 98.8% of motherboards.
PCIe bifurcation support
What it is: Shows whether the board can split PCIe lanes across multiple devices from one slot or link.
When it matters: When you plan multi-SSD adapters or more advanced expansion setups.

Importance: MEDIUM

yes
MSI X399 SLI Plus supports PCIe bifurcation. 39.1% of motherboards support this feature.
Show more
Total USB ports (rear I/O)
What it is: The total number of rear USB ports available on the motherboard.
When it matters: When you use many USB devices directly from the back of the PC.

Importance: MEDIUM

Good value: >=8

12
MSI X399 SLI Plus has 12 USB ports (rear I/O), which is more than 93% of motherboards and equal to 5.5% of motherboards.
Total USB ports (including headers)
What it is: The total number of USB ports supported when rear ports and internal headers are counted together.
When it matters: When you want to know the board's full USB expansion potential.

Importance: MEDIUM

Good value: >=14

21
MSI X399 SLI Plus has 21 USB ports (including headers), which is more than 95% of motherboards and equal to 2.7% of motherboards.
Total USB-C ports (rear I/O)
What it is: The total number of rear USB-C ports on the motherboard.
When it matters: When you want more USB-C devices connected without adapters.

Importance: MEDIUM

Good value: >=1

1
MSI X399 SLI Plus has 1 USB-C ports (rear I/O), which is more than 35.4% of motherboards and equal to 48.8% of motherboards.
Total USB-C ports (including headers)
What it is: The total number of USB-C ports supported when rear ports and internal headers are counted together.
When it matters: When you want more USB-C connectivity across the whole build.

Importance: MEDIUM

Good value: >=2

2
MSI X399 SLI Plus has 2 USB-C ports (including headers), which is more than 51.8% of motherboards and equal to 32.8% of motherboards.
N. of USB 3.2 Gen2x2 ports (USB-C)
What it is: The number of rear USB 3.2 Gen2x2 Type-C ports on the motherboard.
When it matters: When you want very fast USB-C connectivity on the rear I/O.

Importance: HIGH

Good value: >=1

0
MSI X399 SLI Plus has 0 USB 3.2 Gen2x2 ports (USB-C), which is equal to 81.6% of motherboards.
Show more
LAN speed
What it is: The maximum wired Ethernet speed supported by the motherboard.
When it matters: When you want faster wired networking.

Importance: HIGH

Good value: 2.5GbE

1 Gbps
MSI X399 SLI Plus supports LAN speeds up to 1 Gbps, which is lower than that of 50.8% of motherboards and equal to that of 49.1% of motherboards.
LAN controller
What it is: The model of onboard Ethernet controller used by the motherboard.
When it matters: When you compare networking hardware quality and features.

Importance: MEDIUM

?
N. of RJ45 ports
What it is: The number of wired Ethernet ports on the motherboard.
When it matters: When you need one or more wired network connections.

Importance: LOW

1
MSI X399 SLI Plus has 1 RJ45 ports, which is equal to 85.6% of motherboards.
Wi-Fi connectivity
What it is: Shows whether the motherboard includes onboard Wi-Fi hardware instead of requiring a separate adapter.
When it matters: When you want wireless networking without adding an extra card.

Importance: MEDIUM

no
MSI X399 SLI Plus does not support Wi-Fi connectivity. 49.1% of motherboards support this feature.
Wi-Fi version
What it is: The supported Wi-Fi generation, such as Wi-Fi 6 or Wi-Fi 7.
When it matters: When you care about wireless speed and router compatibility.

Importance: MEDIUM

Good value: Wi-Fi 6E (802.11ax)

N/A
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Audio codec
What it is: The onboard audio codec used by the motherboard.
When it matters: When sound quality from the built-in audio matters to you.

Importance: MEDIUM

Realtek ALC1220
MSI X399 SLI Plus uses the Realtek ALC1220 audio codec, which is more advanced than that of 65.1% of motherboards and equal to that of 13% of motherboards.
Audio channels
What it is: The audio channel configuration supported by the onboard sound solution.
When it matters: When you want surround sound from the motherboard audio outputs.

Importance: LOW

Good value: 7.1

7.1
MSI X399 SLI Plus offers 7.1 audio channels, which is more than 4.9% of motherboards and equal to 95.1% of motherboards.
Audio SNR
What it is: The signal-to-noise ratio of the onboard audio solution.
When it matters: When you care about cleaner onboard audio output.

Importance: MEDIUM

Good value: >=120 dB

120 dB
MSI X399 SLI Plus has an audio SNR of 120 dB, which is higher than that of 55% of motherboards and equal to that of 41.5% of motherboards.
Headphone amp support
What it is: Shows whether the onboard audio path includes dedicated headphone amplification for harder-to-drive headsets.
When it matters: When you use harder-to-drive headphones from the onboard audio.

Importance: LOW

yes
MSI X399 SLI Plus supports a headphone amp. 37% of motherboards support this feature.
supports up to 600Ω.
N. of 3.5mm audio jacks
What it is: The number of rear 3.5mm audio jacks on the motherboard.
When it matters: When you want more analog audio connection options.

Importance: LOW

Good value: >=5

5
MSI X399 SLI Plus has 5 3.5mm audio jacks, which is more than 49.8% of motherboards and equal to 36.8% of motherboards.
Show more
VRM phases
What it is: The number of power-delivery phases used by the motherboard VRM.
When it matters: When you care about CPU power delivery and overclocking headroom.

Importance: HIGH

Good value: >=12

13
MSI X399 SLI Plus has 13 VRM phases, which is more than 60.8% of motherboards and equal to 0.5% of motherboards.
N. of CPU power connectors
What it is: The number of CPU power connectors on the motherboard.
When it matters: When you care about power delivery for higher-end CPUs.

Importance: HIGH

Good value: >=2

2
MSI X399 SLI Plus has 2 CPU power connectors, which is more than 54.6% of motherboards and equal to 45.3% of motherboards.
Dual 8-pin CPU power.
N. of fan headers
What it is: The number of headers available for case or CPU fans.
When it matters: When your build uses several fans.

Importance: MEDIUM

Good value: >=6

6
MSI X399 SLI Plus has 6 fan headers, which is more than 50.3% of motherboards and equal to 22.3% of motherboards.
Pump header
What it is: Shows whether the motherboard includes a dedicated header designed for a liquid-cooling pump.
When it matters: When you build with an AIO or custom liquid cooling loop.

Importance: MEDIUM

yes
MSI X399 SLI Plus has a pump header. 23.1% of motherboards include this feature.
Pump header max current
What it is: The maximum current the dedicated pump header can supply.
When it matters: When you want to make sure the pump header can power your cooling setup.

Importance: LOW

Good value: >=2 A

2 A
MSI X399 SLI Plus supports up to 2 A on the pump header, which is higher than that of 43.3% of motherboards and equal to that of 33.4% of motherboards.
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MSI X399 SLI Plus vs the average motherboard

  • 4 more rear USB ports
    MSI X399 SLI Plus has more rear USB ports than the average motherboard (12 vs 8). The average motherboard has 8 rear USB port/s.
    What it is: The total number of rear USB ports available on the motherboard.
    When it matters: When you use many USB devices directly from the back of the PC.

    Importance: MEDIUM

    Good value: >=8

    MSI X399 SLI Plus has more rear USB ports than the average motherboard (12 vs 8). The average motherboard has 8 rear USB port/s.12 vs 8
  • 4 more memory slots
    MSI X399 SLI Plus has more memory slots than the average motherboard (8 vs 4). The average motherboard has 4 memory slot/s.
    What it is: The number of RAM slots on the motherboard.
    When it matters: When you want more room for future memory upgrades.

    Importance: HIGH

    Good value: >=4

    MSI X399 SLI Plus has more memory slots than the average motherboard (8 vs 4). The average motherboard has 4 memory slot/s.8 vs 4
  • More flexible PCIe lane configuration
    MSI X399 SLI Plus has more flexible PCIe lane configuration than the average motherboard (x16/x8/x16/x8, x16/x0/x16/x8, x8/x8/x16/x8 vs x16/x1). The average motherboard uses x16/x1 PCIe slot lane configuration.
    What it is: The actual lane wiring used by the motherboard PCIe slots.
    When it matters: When you need to know how much bandwidth each slot really gets.

    Importance: HIGH

    MSI X399 SLI Plus has more flexible PCIe lane configuration than the average motherboard (x16/x8/x16/x8, x16/x0/x16/x8, x8/x8/x16/x8 vs x16/x1). The average motherboard uses x16/x1 PCIe slot lane configuration.x16/x8/x16/x8, x16/x0/x16/x8, x8/x8/x16/x8 vs x16/x1
  • 1 more M.2 sockets
    MSI X399 SLI Plus has more M.2 sockets than the average motherboard (3 vs 2). The average motherboard has 2 M.2 socket/s.
    What it is: The number of M.2 slots available on the motherboard.
    When it matters: When you want room for more NVMe or M.2 drives.

    Importance: HIGH

    Good value: >=3

    MSI X399 SLI Plus has more M.2 sockets than the average motherboard (3 vs 2). The average motherboard has 2 M.2 socket/s.3 vs 2
  • 6 more total USB connections
    MSI X399 SLI Plus has more total USB connections than the average motherboard (21 vs 15). The average motherboard has 15 total USB connections.
    What it is: The total number of USB ports supported when rear ports and internal headers are counted together.
    When it matters: When you want to know the board's full USB expansion potential.

    Importance: MEDIUM

    Good value: >=14

    MSI X399 SLI Plus has more total USB connections than the average motherboard (21 vs 15). The average motherboard has 15 total USB connections.21 vs 15
  • Includes POST code display
    MSI X399 SLI Plus has a POST code display, while the average motherboard does not. 27.2% of motherboards include a POST code display.
    What it is: Shows whether the board includes a diagnostic POST code readout for boot troubleshooting.
    When it matters: When you troubleshoot boot issues and want clearer error information.

    Importance: LOW

    MSI X399 SLI Plus has a POST code display, while the average motherboard does not. 27.2% of motherboards include a POST code display.
  • 1 more CPU power connectors
    MSI X399 SLI Plus has more CPU power connectors than the average motherboard (2 vs 1). The average motherboard has 1 CPU power connectors.
    Dual 8-pin CPU power.
    What it is: The number of CPU power connectors on the motherboard.
    When it matters: When you care about power delivery for higher-end CPUs.

    Importance: HIGH

    Good value: >=2

    MSI X399 SLI Plus has more CPU power connectors than the average motherboard (2 vs 1). The average motherboard has 1 CPU power connectors.2 vs 1
  • Newer CPU socket
    MSI X399 SLI Plus has newer CPU socket than the average motherboard (TR4 vs LGA 1,151). The average motherboard uses LGA 1,151 CPU socket.
    What it is: The socket type the motherboard is built to support.
    When it matters: When you need the motherboard to match a specific CPU.

    Importance: HIGH

    MSI X399 SLI Plus has newer CPU socket than the average motherboard (TR4 vs LGA 1,151). The average motherboard uses LGA 1,151 CPU socket.TR4 vs LGA 1151
  • Includes POST code display
    MSI X399 SLI Plus has a POST code display, while the average motherboard does not. 27.2% of motherboards include a POST code display.
  • Newer CPU socket
    MSI X399 SLI Plus has newer CPU socket than the average motherboard (TR4 vs LGA 1,151). The average motherboard uses LGA 1,151 CPU socket.
  • Rear-panel CMOS reset button
    MSI X399 SLI Plus has a rear-panel CMOS reset button, while the average motherboard does not. 26.5% of motherboards include a rear-panel CMOS reset button.
  • 4 more memory slots
    MSI X399 SLI Plus has more memory slots than the average motherboard (8 vs 4). The average motherboard has 4 memory slot/s.
  • Supports ECC memory
    MSI X399 SLI Plus supports ECC memory, while the average motherboard does not. 20.9% of motherboards support ECC memory.
  • More memory channels
    MSI X399 SLI Plus has more memory channels than the average motherboard (4 vs 2). The average motherboard has 2 memory channel/s.
  • 1 more M.2 sockets
    MSI X399 SLI Plus has more M.2 sockets than the average motherboard (3 vs 2). The average motherboard has 2 M.2 socket/s.
  • 4 more SATA 3 connectors
    MSI X399 SLI Plus has more SATA 3 connectors than the average motherboard (8 vs 4). The average motherboard has 4 SATA 3 connectors.
  • More flexible PCIe lane configuration
    MSI X399 SLI Plus has more flexible PCIe lane configuration than the average motherboard (x16/x8/x16/x8, x16/x0/x16/x8, x8/x8/x16/x8 vs x16/x1). The average motherboard uses x16/x1 PCIe slot lane configuration.
  • 1 more PCIe x1 slots
    MSI X399 SLI Plus has more PCIe x1 slots than the average motherboard (2 vs 1). The average motherboard has 1 PCIe x1 slot/s.
  • 3 more PCIe 3.0x16 slots
    MSI X399 SLI Plus has more PCIe 3.0x16 slots than the average motherboard (4 vs 1). The average motherboard has 1 PCIe 3.0x16 slot/s.
  • 4 more rear USB ports
    MSI X399 SLI Plus has more rear USB ports than the average motherboard (12 vs 8). The average motherboard has 8 rear USB port/s.
  • 6 more total USB connections
    MSI X399 SLI Plus has more total USB connections than the average motherboard (21 vs 15). The average motherboard has 15 total USB connections.
  • 1 more USB 3.2 Gen2 USB-C ports
    MSI X399 SLI Plus has more USB 3.2 Gen2 USB-C ports than the average motherboard (1 vs 0). The average motherboard has 0 USB 3.2 Gen2 USB-C port/s.
  • 1 more USB 3.2 Gen1 headers
    MSI X399 SLI Plus has more USB 3.2 Gen1 headers than the average motherboard (2 vs 1). The average motherboard has 1 USB 3.2 Gen1 header/s.
  • 4 more USB 3.2 Gen1 ports
    MSI X399 SLI Plus has more USB 3.2 Gen1 ports than the average motherboard (8 vs 4). The average motherboard has 4 USB 3.2 Gen1 port/s.
  • 1 more USB 3.2 Gen2 headers
    MSI X399 SLI Plus has more USB 3.2 Gen2 headers than the average motherboard (1 vs 0). The average motherboard has 0 USB 3.2 Gen2 header/s.
  • 1 more total USB-C connections
    MSI X399 SLI Plus has more total USB-C connections than the average motherboard (2 vs 1). The average motherboard has 1 total USB-C connections.
  • Better audio codec
    MSI X399 SLI Plus has better audio codec than the average motherboard (Realtek ALC1,220 vs Realtek ALC898). The average motherboard uses Realtek ALC898 audio codec.
  • 5 dB higher audio SNR
    MSI X399 SLI Plus has a higher audio SNR than the average motherboard (120 dB vs 115 dB). The average motherboard has audio SNR of 115 dB.
  • 1 more CPU power connectors
    MSI X399 SLI Plus has more CPU power connectors than the average motherboard (2 vs 1). The average motherboard has 1 CPU power connectors.
  • More VRM phases
    MSI X399 SLI Plus has more VRM phases than the average motherboard (13 vs 10). The average motherboard has 10 VRM phase/s.
  • 1 more fan headers
    MSI X399 SLI Plus has more fan headers than the average motherboard (6 vs 5). The average motherboard has 5 fan header/s.
  • More basic motherboard chipset
    MSI X399 SLI Plus has more basic motherboard chipset than the average motherboard (AMD X399 vs Intel B860). The average motherboard uses Intel B860 chipset.
  • No integrated graphics support
    MSI X399 SLI Plus does not support integrated graphics, while the average motherboard does. 89.4% of motherboards support integrated graphics.
  • 4 years older release date
    MSI X399 SLI Plus is older than the average motherboard (2,017 vs 2,021). The average motherboard was released in 2,021.
    October 2017
  • 21.7% lower maximum RAM speed
    MSI X399 SLI Plus has a lower maximum RAM speed than the average motherboard (3,600 MT/s vs 4,600 MT/s). The average motherboard supports RAM speed of 4,600 MT/s.
  • 27% lower overclocked RAM speed
    MSI X399 SLI Plus has a lower overclocked RAM speed than the average motherboard (3,600 MT/s vs 4,933 MT/s). The average motherboard supports overclocked RAM speed of 4,933 MT/s.
  • Fewer RAID options
    MSI X399 SLI Plus has fewer RAID options than the average motherboard (0/1/10 vs 0/1/5/10). The average motherboard has 0/1/5/10 RAID level/s.
    JBOD excluded from RAID-level set
  • 1 fewer DisplayPort outputs
    MSI X399 SLI Plus has fewer DisplayPort outputs than the average motherboard (0 vs 1). The average motherboard has 1 DisplayPort outputs.
    no onboard video outputs
  • 1 fewer HDMI outputs
    MSI X399 SLI Plus has fewer HDMI outputs than the average motherboard (0 vs 1). The average motherboard has 1 HDMI outputs.
  • 60% lower LAN speed
    MSI X399 SLI Plus has a lower LAN speed than the average motherboard (1 Gbps vs 2.5 Gbps). The average motherboard offers LAN speed of 2.5 Gbps.
  • No Wi-Fi antenna included
    MSI X399 SLI Plus does not include a Wi-Fi antenna, while the average motherboard does. 51.1% of motherboards include a Wi-Fi antenna.
  • 1 fewer ARGB headers
    MSI X399 SLI Plus has fewer ARGB headers than the average motherboard (1 vs 2). The average motherboard has 2 ARGB header/s.
  • More basic motherboard chipset
    MSI X399 SLI Plus has more basic motherboard chipset than the average motherboard (AMD X399 vs Intel B860). The average motherboard uses Intel B860 chipset.
    What it is: The chipset that defines the motherboard platform and many of its features.
    When it matters: When you compare platform features, connectivity, and CPU support.

    Importance: HIGH

    MSI X399 SLI Plus has more basic motherboard chipset than the average motherboard (AMD X399 vs Intel B860). The average motherboard uses Intel B860 chipset.AMD X399 vs Intel B860
  • 60% lower LAN speed
    MSI X399 SLI Plus has a lower LAN speed than the average motherboard (1 Gbps vs 2.5 Gbps). The average motherboard offers LAN speed of 2.5 Gbps.
    What it is: The maximum wired Ethernet speed supported by the motherboard.
    When it matters: When you want faster wired networking.

    Importance: HIGH

    Good value: 2.5GbE

    MSI X399 SLI Plus has a lower LAN speed than the average motherboard (1 Gbps vs 2.5 Gbps). The average motherboard offers LAN speed of 2.5 Gbps.1 Gbps vs 2.5 Gbps
  • No Wi-Fi antenna included
    MSI X399 SLI Plus does not include a Wi-Fi antenna, while the average motherboard does. 51.1% of motherboards include a Wi-Fi antenna.
    What it is: Shows whether the external Wi-Fi antenna is included with the motherboard package.
    When it matters: When the board has Wi-Fi and you want it ready to use right away.

    Importance: LOW

    MSI X399 SLI Plus does not include a Wi-Fi antenna, while the average motherboard does. 51.1% of motherboards include a Wi-Fi antenna.
  • No integrated graphics support
    MSI X399 SLI Plus does not support integrated graphics, while the average motherboard does. 89.4% of motherboards support integrated graphics.
    What it is: Shows whether the motherboard can output video from CPUs that include integrated graphics.
    When it matters: When you want video output without installing a graphics card.

    Importance: MEDIUM

    MSI X399 SLI Plus does not support integrated graphics, while the average motherboard does. 89.4% of motherboards support integrated graphics.
  • Fewer RAID options
    MSI X399 SLI Plus has fewer RAID options than the average motherboard (0/1/10 vs 0/1/5/10). The average motherboard has 0/1/5/10 RAID level/s.
    JBOD excluded from RAID-level set
    What it is: The RAID modes officially supported by the motherboard storage platform.
    When it matters: When you plan to use multiple drives in a RAID setup.

    Importance: MEDIUM

    MSI X399 SLI Plus has fewer RAID options than the average motherboard (0/1/10 vs 0/1/5/10). The average motherboard has 0/1/5/10 RAID level/s.0/1/10 vs 0/1/5/10
  • 1 fewer DisplayPort outputs
    MSI X399 SLI Plus has fewer DisplayPort outputs than the average motherboard (0 vs 1). The average motherboard has 1 DisplayPort outputs.
    no onboard video outputs
    What it is: The number of DisplayPort video outputs on the motherboard.
    When it matters: When you want to connect compatible displays through the rear I/O.

    Importance: MEDIUM

    Good value: >=1

    MSI X399 SLI Plus has fewer DisplayPort outputs than the average motherboard (0 vs 1). The average motherboard has 1 DisplayPort outputs.0 vs 1
  • 1 fewer ARGB headers
    MSI X399 SLI Plus has fewer ARGB headers than the average motherboard (1 vs 2). The average motherboard has 2 ARGB header/s.
    What it is: The number of 3-pin addressable RGB headers available on the motherboard.
    When it matters: When you want to connect more ARGB lighting devices.

    Importance: LOW

    Good value: >=2

    MSI X399 SLI Plus has fewer ARGB headers than the average motherboard (1 vs 2). The average motherboard has 2 ARGB header/s.1 vs 2
  • 1 fewer HDMI outputs
    MSI X399 SLI Plus has fewer HDMI outputs than the average motherboard (0 vs 1). The average motherboard has 1 HDMI outputs.
    What it is: The number of HDMI outputs on the motherboard.
    When it matters: When you plan to use integrated graphics with one or more HDMI displays.

    Importance: MEDIUM

    MSI X399 SLI Plus has fewer HDMI outputs than the average motherboard (0 vs 1). The average motherboard has 1 HDMI outputs.0 vs 1

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Third-party reviews

United States

(Reviews last updated: May 2026)

What customers like about MSI X399 SLI Plus?

  • Excellent value for the price, lowering the barrier of entry for the X399 platform
  • Premium feature set including 128GB quad-channel DDR4 support and triple M.2 slots
  • Highly functional VRM with 13 phases that provides stable power delivery for Threadripper CPUs
  • User-friendly BIOS (Click BIOS 5) with an easy-to-use 'Game Boost' overclocking knob
  • Flashback+ feature allows for BIOS updates without a CPU installed, which is crucial for newer chip compatibility
  • Clean, professional all-black aesthetic with customizable RGB lighting via Mystic Light
  • Extensive connectivity with 12 rear USB ports and dual 8-pin CPU power connectors

What customers dislike about MSI X399 SLI Plus?

  • VRM can reach high temperatures (up to 96°C-100°C) under extreme loads with high-core count CPUs like the 2990WX
  • Requires immediate BIOS updates out of the box for stability and compatibility with 2nd Gen Threadripper CPUs
  • Some users reported occasional stability issues, including BSODs or freezes related to sensitive RAM timings
  • Cramped board layout near the top due to the eight DIMM slots and dual power connectors, making some installations tight
  • The CMOS battery is difficult to access, sometimes requiring significant effort or wire-cutting to replace
  • Missing a riser plug for the case front-panel headers (power/reset pins), making that connection less intuitive

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