Best Logitech ergonomic mice in 2026 (1+ compared)

The main Logitech ergonomic mouse series are as follows.

• Ergo M575 and M575s: This branch covers Logitech's more accessible thumb-trackball ergonomic models. These mice are built around reduced arm movement, 2000 DPI-class tracking, Bluetooth / 2.4 GHz connectivity, and a simpler mainstream ergonomic price point.
• Mx Ergo and Mx Ergo S: This is Logitech's more advanced ergonomic trackball branch. These models are heavier, use 8 buttons instead of 5, and target users who want a richer control layout and a more committed ergonomic desk setup.
• Lift Vertical and Mx Vertical: Logitech's vertical line focuses on wrist-angle changes rather than trackball control. These models move up to 4000 DPI, use 6 buttons, and position themselves as comfort-led alternatives for users who prefer a more conventional cursor movement style.

Logitech ergonomic mice are unusual because the lineup is split across two different ergonomic ideas rather than one. In practice, buyers are choosing first between trackball ergonomics and vertical ergonomics, and only then between cheaper and more premium versions inside each branch.

The best Logitech ergonomic mice usually cost about £35-£100. In practical terms, that places Logitech in the mid-range office-comfort segment, with mainstream ergonomic entry points around £35-£45 and more premium specialized models climbing toward £70-£100.

Logitech ergonomic mouse pricing is driven mainly by ergonomic approach and feature depth. The cheaper end is led by simpler Ergo M575-style trackballs, the mid-tier is occupied by Lift Vertical and Mx Ergo models around £60-£70, and the top end is pushed by Mx Vertical at roughly £100 as the more premium full-size vertical option.

This chart visualizes Logitech ergonomic mouse prices.

Logitech ergonomic mice usually compare with Microsoft models as the more specialized and more ergonomics-led option, while Microsoft is the more conventional mainstream desktop brand. Logitech is stronger if you specifically want trackball or vertical designs rather than just a standard productivity mouse with familiar branding.

The technical split makes that difference clear. Logitech's ergonomic range spans roughly £35-£100, includes trackball and vertical shells, uses 5 to 8 buttons, and stays fully focused on wireless productivity use, while Microsoft's mouse range is mostly conventional Bluetooth productivity hardware with 2 to 4 buttons, ambidextrous shapes, and only one obvious wired performance outlier. In practice, Logitech ergonomic mice are the better fit for deliberate comfort-focused setups, while Microsoft models make more sense if you want a simpler standard mouse shape.

The main technical criteria for a Logitech ergonomic mouse are as follows.

• Ergonomic branch: Logitech's ergonomic range splits into two genuinely different control methods: thumb-trackball models such as Ergo and MX Ergo, and vertical models such as Lift and MX Vertical. Go to the trackball side if desk space is limited or you want to reduce arm movement, and stay on the vertical side if you still want normal mouse travel but need a more neutral hand angle.
• Model choice inside the branch: Once the trackball-versus-vertical decision is made, the remaining split is mostly mainstream versus premium. Lift is the easier entry point for a vertical office mouse, MX Vertical is the fuller higher-tier version, and MX Ergo makes sense when you actively want the planted, thumb-driven behavior that a normal moving mouse cannot give you.
• Weight and desk behavior: This category runs roughly 125-259 g, but those numbers behave differently from ordinary mice. The 125-140 g vertical side still moves around the desk like a mouse, while 160 g and above usually signals trackball hardware where the body stays planted and the thumb does more of the pointing work.
• Connection stack: Logitech ergonomic models are mainly Bluetooth / 2.4 GHz devices, with MX Vertical also adding wired use. That makes connectivity a workflow question rather than a speed question: basic dual-mode is enough for most desks, while wired fallback only matters if you want one less thing to think about or switch between.
• Response ceiling: These mice sit around 125 Hz and belong firmly to the comfort-and-productivity tier. If your priority is gaming response, this is the wrong branch; if the goal is to reduce strain while keeping decent office control, the modest polling rate is not the limiting factor.
• Price band: The range forms a real hardware ladder from roughly 40-70 EUR into the 90-120 EUR zone. The money usually buys a different control method, a more refined shell, or fuller connection options, so the right approach is to pay for the ergonomic mechanism you want rather than assuming the most expensive model is automatically the best fit.